Molecular Formula | C13H17NO2 |
Molar Mass | 219.28 |
Density | 1.023±0.06 g/cm3(Predicted) |
Melting Point | 46-49°C |
Boling Point | 160-166 °C(Press: 6 Torr) |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White to Pale Yellow |
Storage Condition | Sealed in dry,Room Temperature |
Physical and Chemical Properties | Crystalline compound. The melting point is greater than 50°C. |
Hazard Class | IRRITANT |
chemical properties | crystalline compound. The melting point is greater than 50°C. |
Use | Verapamil intermediate. |
production method | using guaiacol as raw material, methylation with dimethyl sulfate under the action of sodium hydroxide to generate o-dimethoxybenzene, and then chloromethylation with formaldehyde and concentrated hydrochloric acid to obtain 3, 4-dimethoxybenzyl chloride, the latter is heated with sodium cyanide, and dimethoxybenzonitrile is obtained after cyanidation, then it is condensed with bromoisopropane with sodium hydroxide (isopropylation) to produce the product. |